Upon joining the Santa Maria degli Angeli monastery at the age of 20, he changed his name to Lorenzo Monaco – or rather, Lawrence the Monk.
Working throughout the late Gothic/early Renaissance period, Monaco is known as creating many spiritual works. Despite not being one to adopt more modern techniques arising during his lifetime, such as developments in perspective, he was a popular artist that received many commissions.
His works can be found in the Accademia di Belle Arti di Firenze, Uffizi Gallery and Santa Trinità church in Florence to name a few.
He died in 1425, which according to local artist and gossip Vasari, was due to some kind of infection or tumor.